Isoniazid- and rifampicin-induced thrombocytopenia
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چکیده
منابع مشابه
Isoniazid- and rifampicin-induced thrombocytopenia
Treatment of tuberculosis has many side effects. Thrombocytopenia is a serious side effect of such treatment and occurs mostly due to rifampicin (RIF). There are very few reported cases of thrombocytopenia due to isoniazid (INH). An 18-year-old female patient was diagnosed with smear-positive pulmonary tuberculosis. A four-drug regimen [INH, RIF, ethambutol (EMB), and pyrazinamide (PZA)] was gi...
متن کاملRifampicin induced thrombocytopenia.
Rifampicin occasionally causes thrombocytopenia when given as part of an intermittent regimen. A case is reported of severe thrombocytopenia developing after one dose of rifampicin, following a 4-month gap in daily therapy. The literature on rifampicin-induced thrombocytopenia is reviewed.
متن کاملRifampicin induced thrombocytopenia.
Thrombocytopenia is an uncommon but potentially life threatening complication of certain anti-tubercular drugs and is characterized by rapid destruction of platelets whenever an offending drug is taken by a susceptible person. Here is a case report of Rifampicin induced Thrombocytopenia. This case is being reported for purpose of its rare occurrence and documentation.
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DW was a born in China with complete unilateral cleft lip and palate. She was placed in an orphanage shortly after birth. At 19 months of age, a family in the United States adopted her, and shortly thereafter, she underwent uneventful cleft lip repair. At 20 months of age she had a positive Mantoux Purified Protein Derivative (PPD) test and was begun on Isoniazid monotherapy for possible latent...
متن کاملRifampicin and isoniazid prophylactic chemotherapy for tuberculosis.
Prophylaxis of tuberculosis in children with four month (n = 53) and three month regimens (n = 213) of rifampicin and isoniazid from 1987 to 1996 were tolerated without any toxicity. The reduction in the proportion of paediatric tuberculosis, which was seen after the introduction of chemoprophylaxis with longer regimens in 1981, was maintained with the shorter duration regimens. Altered immigra...
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ژورنال
عنوان ژورنال: Multidisciplinary Respiratory Medicine
سال: 2013
ISSN: 2049-6958
DOI: 10.1186/2049-6958-8-13